Los Portales Family Medicine

Caring for the community


John W. Pierce,  MD

Dr. Pierce is board certified in Internal Medicine and has been serving the Mission and Noe Valley communities for over twenty years. He specializes in primary care, internal medicine, and adult non-surgical medicine. He is affiliated with St. Luke's Hospital in the Mission District, and with Seton Medical Center in Daly City.

Los Portales Family Medicine is located in the heart of the Mission District between 20th and 21st street.

  • There are multiple other services on-site including Rehabilitative Medicine, Podiatry, Optometry, Dermatology, and Pharmacy.

  • His office staff speaks Spanish and Tagalog.

  • Street parking and garage parking at Mission St. Garage on 21st and Valencia Street are available.

  • Los Portales Family Medicine is located at:

2480 Mission St.
Suite 329
San Francisco, CA 94110

Phone: (415) 826-2438
Fax: (415) 826-2702

Office Hours: M-F 9am-6pm
Closed for lunch between 1-2


John W. Pierce, MD
Board Certified in Internal Medicine
Tufts University School of Medicine


Daniel E. Chan, PA-C
Physician's Assistant Certified
Stanford University PA Program


  Los Portales Medical Building

Email Dr. Pierce

Directions to Office

St. Luke's Hospital

Seton Medical Center

Family Doctor

Medical Resources